pegfp c1 ataxin3 q84 Search Results


pegfp ataxin3 q84  (Addgene inc)
92
Addgene inc pegfp ataxin3 q84
Pegfp Ataxin3 Q84, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pcmv dr.− 8.92  (Matos labs)
90
Matos labs pcmv dr.− 8.92
Pcmv Dr.− 8.92, supplied by Matos labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasmids pegfp ataxin3 q28  (Addgene inc)
92
Addgene inc plasmids pegfp ataxin3 q28
Plasmids Pegfp Ataxin3 Q28, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pegfp q23  (Addgene inc)
94
Addgene inc pegfp q23
Pegfp Q23, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pegfp q74  (Addgene inc)
94
Addgene inc pegfp q74
Pegfp Q74, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hek293 cells  (Addgene inc)
93
Addgene inc hek293 cells
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
Hek293 Cells, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+ataxin3+q84/pAG415GPD-ccdB-HA+(Plasmid+%2314242)/pmc10698508-393-0-14
Average 93 stars, based on 1 article reviews
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pcdna3 1 n ha vector  (Addgene inc)
96
Addgene inc pcdna3 1 n ha vector
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
Pcdna3 1 N Ha Vector, supplied by Addgene inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
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pegfp c1 ataxin 3 q84  (Addgene inc)
93
Addgene inc pegfp c1 ataxin 3 q84
A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in <t>HEK293</t> cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.
Pegfp C1 Ataxin 3 Q84, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pegfp+c1+ataxin3+q84/EGFP-C1+(Plasmid+%2354621)/pm28223212-43-3-8
Average 93 stars, based on 1 article reviews
pegfp c1 ataxin 3 q84 - by Bioz Stars, 2026-10
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Image Search Results


A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in HEK293 cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.

Journal: Molecular Systems Biology

Article Title: A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration

doi: 10.15252/msb.202311801

Figure Lengend Snippet: A Cell viability at the indicated concentrations of SC79 (0.1–100 μM), an Akt1 activator, in HEK293 cells. Data are the mean and SEM of biological replicates ( n = 4–10). * denotes P ‐value < 0.05 (Student's t ‐test). B–E Determination of the alleviating effect of SC79 (1 or 10 μM) on cell death in human cell‐based models for AD (B), HD (C), SCA1 (D), and SCA3 (E). Data are the mean and SEM of biological replicates ( n = 3–7). * denotes P ‐value < 0.05 (Student's t ‐test). F, G SC79 was administered to 7‐month‐old AD mice for 1 month, and their memory remedy was investigated by Barnes Maze Test. For 5 days, the time to find a target hole decreased due to learning. The mice were tested on day 15 and 16 after a blank period to investigate long‐term memory. The time to find a target hole on tested days (F) and the average of latencies on days 15 and 16 (G) are shown. Data are the mean and SEM of three biological replicates. * denotes P ‐value < 0.05 (Student's t ‐test). H The dysregulated anxiety levels in AD mice were investigated using the elevated plus maze test. In (G) and (H), + and – denote the treatment and nontreatment with SC79, respectively. Bar graphs were drawn from at least three independent experiments (biological replicates) and represent mean and SEM. * denotes P ‐value < 0.05 (Student's t ‐test). Source data are available online for this figure.

Article Snippet: HEK293 cells having 70–80% cell density were transiently transfected with pEGFP‐C1‐Aβ 1‐42 , pEGFP‐Htt‐exon1‐Q74 (Addgene #40262), pEGFP‐Ataxin1‐52Q (Addgene #32492), or pEGFP‐C1‐Ataxin3‐Q84 (Addgene #22123) DNA using Lipofectamine 2000 (Invitrogen, CA, USA) following the manufacturer's instructions.

Techniques:

Journal: Molecular Systems Biology

Article Title: A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration

doi: 10.15252/msb.202311801

Figure Lengend Snippet:

Article Snippet: HEK293 cells having 70–80% cell density were transiently transfected with pEGFP‐C1‐Aβ 1‐42 , pEGFP‐Htt‐exon1‐Q74 (Addgene #40262), pEGFP‐Ataxin1‐52Q (Addgene #32492), or pEGFP‐C1‐Ataxin3‐Q84 (Addgene #22123) DNA using Lipofectamine 2000 (Invitrogen, CA, USA) following the manufacturer's instructions.

Techniques: Over Expression, Plasmid Preparation, Construct